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The entire C-terminal conserved region is about 38 amino acids in length, but the upstream portions of the VSPs can be highly different, allowing the organism to expose very different antigens to the host.
However, we found that for other biological networks, the C(k) curve can be highly different with random networks of same degree distribution (for example, the protein-protein interaction network and the genetic synthetic lethal network. Additional file 1: Figure S1), suggesting that the variation of C(k) cannot be solely attributed to the existence of super-hubs.
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Such an approach can be highly inefficient, since different test statistics require different numbers of permutations.
Recent reports indicate that analysis of ki67 can be highly variable between different readers and at different institutions [ 27].
miRNA sequences can be highly conserved across different species, but this does not imply that their target sites are necessarily similarly conserved in sequence.
Our experience shows that with target gene capture followed by deep sequencing (~1,000×), the normalized coverage depth of a particular exon can be highly consistent among different samples.
The measurement of methylation patterns in six distinct tissue types showed that methylation of pseudogenes can be highly variable in different tissues and suggested that methylation of CpG sites may be differentially regulated in these tissues.
Therefore, the simple unweighted topology can be highly informative for different purposes, one of them being the prediction of new interactions or alternatively, as recently shown, the structural controllability of any complex network (Liu et al., 2011).
Finally, we show that these same mutations can be highly deleterious with different genetic backgrounds and environmental conditions, thereby providing glimpses into the prevalence of epistasis and pleiotropy for even well-characterized mutations.
Although the two types of structural information can be highly correlated, they are different, which can capture different aspects of structural feature.
Primary election campaigns can be highly unequal too, with different candidates pouring their efforts into different states.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com