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We further demonstrated that this interaction can be competed more efficiently by a DNA with four-way junction structure than by a linear double-stranded DNA.
The pocket is normally occupied by a mixture of unidentified, fatty acid-like moieties, which can be competed out by a family of capsid-binding, antiviral compounds.
Others should be able to ask us if a particular area can be competed for – and if it can't be, we would have to justify clearly why.
Accusations aside, the first day of fencing at the Summer Olympics demonstrated that organized dueling can be competed with ferocious, hockeylike aggression and accompanied by fevered fan reaction.
When used in a competitive manner, covalent ligands can be competed against reactivity-based probe binding to druggable hotspots to pharmacologically target undruggable proteins.
One of chromenylchalcones tested here, chromenylchalcone 11, showed IC50 of 93.1 nM which can be competed with the IC50 values of well-known flavonoids such as catechin gallate and epicatechin gallate.
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"Some of these roles he has to play can be competing," he said.
You can't go out there when someone else can be competing at full strength".
The performance of interconnection networks is significantly affected by router speed and routing adaptivity, which can be competing factors.
Thus, O-GlcNAcylation and phosphorylation can be competing modifications, and it is known that O-GlcNAcylation protects a variety of proteins from ubiqitination and proteasomal degradation36.
Software that combines and analyzes spatial data is increasingly accessible and used in planning for EBM to strike a balance between what can be competing conservation and development objectives12.
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