Sentence examples for can be alternatively modified from inspiring English sources
Indeed, PCNA can be alternatively modified on the very same residue by either SUMO, a single ubiquitin moiety or by a specific (lysine63-linked) poly-ubiquitin chain (Hoege et al, 2002).
Taking into consideration residues that can be alternatively modified the "conserved face" displays 28 possible modifications amongst 19 residues, while the "variable face" supports a total of 53 modifications.
Alternatively, NEMO itself can be modified by linear ubiquitin chains on the specific Lys residues in the CC2-LZ domain (Tokunaga et al., 2009).
Alternatively, the N-terminal of the Hh signaling protein can be modified by the Rasp protein, another member of the segment polarity genes that is catalytically active as an acyltransferase [ 26].
This can be made with modified microbes.
Alternatively, as depicted in Figure 3D, repressive-marked histones may be exchanged with newly synthesised histones or histone variants that can be modified with activation marks, such as methylation of lysine 4 and histone hyperacetylation.
By identifying proteins involved in dynamic redox processes and the environmental conditions that perturb their balance, novel strategies can be applied to modify target organisms, or alternatively, optimize culture conditions for efficient production of target molecules.
Alternatively, direct covalent conjugation with DNA can be achieved by modifying cysteine (Cys) or Lys residues via disulfide or maleimide coupling, as well as by bioorthogonal chemistry, such as expressed protein ligation, Staudinger ligation and Huisgen cycloaddition.
