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Its binding protein CPEB can assemble complexes that repress mRNA translation as reported in immature oocytes, or that direct cytoplasmic polyadenylation and activate translation e.g. in maturing oocytes [43], [44].
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Proteins containing these domains, which include the ARF (adenosine-ribosylation factor) family, small GTPases like Rac, and guanine exchange factors, can assemble multiprotein complexes and preferentially target these complexes toward a curved membrane, thereby affecting protein localization and signaling.
This is possible because Fab fragments do not require as much processing by the producer cells as do full-length mAbs: bacterial cells cannot glycosylate nor can they assemble complex multichain macromolecules.
It has been shown previously that TRPM6 can assemble into complexes with TRPM7, at least in co-expression studies [ 15, 32].
At the other end of the scale, she can assemble a complex fleet of ingredients that seem to be headed for a nasty collision and send them whizzing around the racetrack.
For the small ribosomal subunit, mutations in the decoding site of the 18S rRNA lead to 40S complexes that can assemble into 80S complexes on the translation start site, but appear to be blocked for subsequent elongation (Lariviere et al. 2006).
Some folds can assemble into protein complexes, such as the homoxehamer of the above-mentioned enzyme.
The results provide insight into how IHF can assemble specific regulatory complexes in the background of extensive nonspecific DNA condensation.
These data indicate that in the absence of the MICOS complex, respiratory complexes can assemble, but do not function optimally.
Scanning the whole surface of the wave front by such a series of the PSA plates, we can assemble the extracted complex amplitude to a two-dimensional discrete distribution of the sampled wave front covering the entire PSA plate plane in the scanning consequence.
One of the least understood and most central questions confronting biologists is how initially simple clusters or sheet-like cell collectives can assemble into highly complex three-dimensional functional tissues and organs.
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