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CaM quantification of SSc-ILD can be useful in the assessment of extent of lung disease and may provide reliable tool in daily clinical practice and clinical trials.
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To evaluate the performance of a computerized-aided method (CaM) for quantification of interstitial lung disease (ILD) in patients with systemic sclerosis and to determine its correlation with the conventional visual reader-based score (CoVR) and the pulmonary function tests (PFTs).
Taking into account this information we designed the present study aimed to evaluate the performance of a computerized-aided method (CaM) for the quantification of ILD, in patients with SSc and to determine its correlation with respect to both the conventional visual reader-based score (CoVR) and the PFTs findings.
The combined delivery of FGF-2 and VEGF through starPEG-heparin hydrogels resulted in pro-angiogenic effects in vitro (study of cell survival/proliferation, morphology and migration) and in vivo (quantification of CAM vascularization) being clearly superior over those of the administration of single factors.
(G ) Quantification of CAM-1 YFP CAM-1 YFPce intensity in the dendrite (n = 20).
Therefore, the discrepancy of quantification between the CaM scoring systems and CoVR method may be intrinsic to the densitometric analysis.
For quantification of L1-CAM immunoreactivity in the spinal cord, 10 sections of the spinal cord were randomly selected from each rat (n = 4 for each group).
The quantification of the L1-CAM-ir buttons revealed that the accumulation of L1-CAM in the dorsal horn became significant at 7 days after SCNT and kept the increase at 20 days (n = 4 at each time point).
Quantification of the L1-CAM-ir ring structures revealed that the SB203580 treatment had no effect on the formation of L1-CAM-ir ring structures after SCNT (P > 0.05, Fig. 10C).
To assess whether K02288 may interfere with angiogenesis in vivo, we used chick embryo chorioallantoic membrane (CAM) models which allow easy visualisation and quantification of angiogenesis.
D. Representative images (left) and quantification (right) of neovessels formed in the CAM assay when stimulated by CM derived from the indicated cells.
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