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The binding mode is somewhat unexpected; while the '1-10' and '1-14' modes are the most common for CaM ligands (the numbering originating from the relative positions in the primary sequence of large hydrophobic residues that bind to the two hydrophobic pockets of CaM), in the case of the CnA-CBD, the binding mode is '1-11'.
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In the case of CaM, although CaM interacts with many of types of proteins, only two interacting partners were counted (Ca 2+ and another protein).
In the case of CaM binding prediction in A. thaliana using cascaded classification, we performed a nested (5-fold) grid search within each cross-validation fold for selecting the parameter values of the second-stage SVM.
In the case of CAM, there was a remarkable association of the use and willingness to present on another occasion for special counselling, possibly reflecting the strongest health-belief of the fields studied here.
One example of a non-classical mode of CaM-peptide interaction has been suggested in the case of the calmodulin-binding domain (CBD) of calcineurin A (CnA).
As the Ca2+-sensing domain, we used a Ca2+ binding protein, calmodulin (CaM), and its target peptide, M13, as in the case of the well-known FRET-based Ca2+ indicator, cameleon [11].
Where a comparison involved more than two groups (as in the case of comparing CAM category scores, scores across media outlets, scores during the first and second time period, and clinical outcome category scores) one-way analysis of variance was used.
In a similar sense, it was reported that the range-separated CAM-B3LYP functional outperformed the PBE0 functional in the case of delocalized excited states.
An example is lack of any safety information in the case of use of CAM during pregnancy where caution is advised.
In the case of overlapped harmonics, the CAM principle (which is further explained in Subsection 4.3) is applied in a least square estimation.
In the case of malignant transformation, alterations of CAM expression and function occur.
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