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Energized by playful spirits and reveries of idyllic sledventures of winters' past, my excitement built all day, challenged only by unsolicited calls of caution -- endless tales of crashes and line-ups of ambulances at the helm.
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However, interpretation of experiments involving established cell lines calls for caution because of possible genetic drift and altered properties.
In this regard, the loss of diversity with the expansion of chondrocytes (the first cluster explained more than three-quarters of the variance in expanded cells) further calls for caution with extrapolation of the results of chondrocyte culture to clinical OA, even if the cells are redifferentiated as in our culture model.
Thus, there is an increased risk of nosocomial infection which calls for caution in the use of RTX in the context of a previous prolonged hospitalization.
Low number of study subjects calls for caution when comparing the magnitudes of odd ratios.
Also, the fact that positive selection appears to have originated in at least three closely related lineages of Sileneae calls for caution when interpreting plastid data at population and phylogenetic levels (cf. [9]).
The questionable reliability and low sensitivity and specificity call for caution of interpretation and further evaluation of the usefulness of this variable.
It also calls for caution in interpretation of results and applications of behavioral theories.
In addition, QNBC/5NPs comprised about 6~8% of breast cancers in publicly available breast cancer datasets The QNBC/5NP subtype is a worse prognostic subgroup of TNBCs, especially in higher stage and this result may be related to adjuvant chemotherapy benefit of BLBCs, calling for caution in the identification of subgroups of patients for therapeutic classification.
How this impacts the results is unclear, and calls for caution in interpretation of the results.
Still, the relatively low number of patients studied calls for caution in the conclusion regarding negative findings.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com