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The identification of indel mutations of even a few base pairs is potentially very challenging, although this is often primarily a mapping rather than calling problem.
To partially overcome this common mapping/SNP calling problem we proposed to combine the advantages of WG mapping (lower false positive SNP detection rate) with TR mapping (faster processing with higher SNP detection rate) and developed our novel 'two-step' mapping approach.
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Thereby, it avoids homopolymer calling problems at the cost of being capable of sequencing only shorter fragments.
I'm listening to a new West Coast rapper at the moment called Problem.
Collectively the gigantic silk screens of Old Hollywood head shots are called "Problem Paintings," which is the show's title.
On the day of my visit, the The Lighthouse Group students were working on an Asdan unit called problem solving.
Strawson's purpose is to dissolve the so called problem of determinism and responsibility.
This theoretical framework permits to generalize different problems, including ours (called problem 2 in [19]).
The boundary value problem (1.1) (or (1.4)), (1.10) will be called Problem.
We call problem (4.1), a generalized set-valued variational-like inclusion problem.
However, Kazmi and Khan [20] called problem (1.2) the generalized system (for short, GS).
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