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The resilient modulus introduced in the design's internal calculations is calculated using Equation 4.
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All MMP calculations were calculated using the algorithm proposed by Hussain and Rea [25].
Strain rate sensitivity (m) and activation volume (V*) calculations were calculated from constant strain rate (CSR) nanoindentation experiments, revealing that dislocation interaction with lamellae interfaces become the rate-limiting step for the strength-ductility trade-off in these EHECs.
All of the statistical calculations were calculated by one-way ANOVA followed by Bonferroni post-hoc test for multigroup comparisons (StatView 5.0; SAS Institute, Cary, NC).
Timeliness calculations were calculated at the benchmark specificity values of 0.85 and 0.97.
Post-hoc power calculations were calculated with GPower Analysis Version 2.0 [ 29].
Power and sample size calculations were calculated retrospectively using G*Power 3.1.2.
All other statistical calculations were calculated in a pairwise manner using two tailed Student's t-tests.
Bootstrap calculations were calculated using PHYML [ 13] (settings, 4 categories, Γ law, JTT model of evolution) and CONSENSE [ 14] for each of the 31 markers.
Sample size calculations were calculated for time to completion of treatment for diagnosed cancer patients, specifically to assess differences between the intervention and control groups in the proportion of patients who complete treatment at nine months.
Bias of the LOEM calculation is calculated as bias = Ctem − Cte/Ctem × 100.
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