The statistical model used was not stated by two studies, results from the statistical calculations were missing for another one.
Sample size calculations were missing for some studies, 25 26 27 and the calculations were based on the endpoint bacteriuria rather than symptomatic urinary tract infection for another study.
In 26% of the published papers, data on sample size calculations were missing and discrepancies between sample size reporting in http://ClinicalTrials.gov and published trials existed.
However, this cost/benefit calculation is missing a component: the cost to the recipient.
Additional subjects were excluded from the reanalysis if residential information necessary for the EPANET exposure calculation was missing (n = 19).
WFIRS-P domain or total scores were considered invalid if more than 30%% of the item scores used for calculation were missing or 'not applicable' (with the exception of one question relating to siblings, for which a score of 'not applicable' could contribute to the minimum number of items).
The main Brazilian ethanol industry organization (UNICA) commented that this study and other calculations of land-use impacts are missing a key factor, the fact that in Brazil "cattle production and pasture has been intensifying already and is projected to do so in the future".
At present only by model calculations like medical decision analysis techniques, e.g. Markov modelling, the time horizon could be extended, but as long as long-time survival and outcome data are missing model calculations will bare a lot of uncertainty.
It is, at present, uncertain whether these stretch modes are missing in the calculations because of an error in the computational treatment or because of inconsistencies in the molecular geometry.
Respondents were sent a list of the data required before the interview and at the interview they were shown the results of the cost benefit calculation to consider whether it accurately reflects the costs and benefits experienced by the establishment (e.g. whether any items are missing in the calculation).
