Table 2 shows an example calculation of relative weightings (W), used to set the target number of matings for each group combination.
As with previous analyses, we were unsuccessful, in attempting to replicate our findings by comparing FC (base on voom with sample quality weighting calculation) for ADT_A versus HC_A for DEGs discovered using cohort C data (correlation 0.44).
All 10 loci appeared to contribute to the assay's accuracy and modified calculations with optimized weightings of genomic loci did not markedly improve accuracy, suggesting that the simple summative model is appropriate to carry forward for clinical work.
Morningstar calculated its sector weightings as of Thursday by using funds' latest available portfolio disclosures.
That suggests they contained risks that JPMorgan's risk-weighting calculations hadn't previously reflected.
A lender with many different types of assets and a big trading operation will be doing thousands of risk-weighting calculations when setting its capital, some of which will involve complex computer models.
This result could be used as an argument in the debate about whether it is appropriate to assign age-related weightings in the calculation of DALYs.
Finally, when a modified ML calculation was tested by using variable weightings for each genomic locus, there was improved performance of ML with an AUC of 0.97, compared with the current method of ML calculation that had an AUC of 0.95.
Worried by the potential for banks to game the calculations that underpin these same risk weightings, regulators this month proposed a higher "leverage ratio", a blunter measure of capital that reflects the overall size of a bank's balance-sheet as well as its riskiness.
The weightings are based on prior calculations of an action's likelihood of leading to a point scoring opportunity, while the human side arises where a particular action - say, kicking a penalty - would give a player a disproportionate score advantage over his teammates who provided him with the opportunity.
