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Prior to descriptor calculation, we generated heuristic 3D conformations with CORINA (Molecular Networks, Erlangen, Germany).
For the wS2 calculation, we generated 100,000 random voxel pairs located within the gray matter of that region.
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By applying a recently developed sequence prediction algorithm and a novel ensemble averaging calculation, we generate a diverse collection of peptide sequences that are predicted to have significant affinity for the protein.
Through this series of calculations, we generated upper and lower ranges of possible IQ decrements for each subpopulation among the most highly exposed children in the 2000 U.S. birth cohort.
We calculated an average number of metal ions per nucleotide from the representative set of 113 crystallographically determined RNA-metal ion complexes (Supplementary Table S1), and in our calculations we generate by default the average number of metal ions plus one.
Since the use of time series data beginning from only one set of initial values easily resulted in numerical calculation errors, we generated additional time series data beginning from 200 sets of initial values that were obtained by slightly perturbing the original data.
To test whether paralogs were significantly enriched in the clusters, we conducted the following background calculation: we first generated, for each cluster, two groups of genes drawn randomly either from the list of 7,405 differentially expressed genes or from genes present on the microarrays used in this study.
For the likelihood calculation, we consider N data generated under x k = (x 1 k, …, x p k ) (1≤ k≤ N) with intervention on J k (where J k = ∅ means no intervention).
To manage the large number of calculations generated, we used a Visual Basic Application (VBA) for Microsoft Excel that automatically calculates the gene-stability value M for every control gene in a given set of samples [ 8].
Depending on whom you talk to, the computer calculation that generated Ms. Cassidy's third strike was discovered either during the championship play or afterward.
The calculation results generated by the onboard S-WPIA and by Katoh et al.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com