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Power calculation: The sample size is calculated on the HF/NS Problem Rating Scale, estimating a mean of 5 (SD = 2.4) and a clinically relevant difference of 2 points [ 9].
In power calculation the sample size and hazard ration (HR) were calculated with a power of 80% and a two-sided level of significance at 0.05.
CL is the statistician who offered advice on the power calculation, the sample size considerations and advice on the statistical methods.
In order to decrease the influence of the variables unknown at the moment of sample calculation, the sample size was increased to 80 subjects.
Given that there was no data available to conduct a standard sample size calculation, the sample size estimate was based on a similar study looking at kinematics in a head reorientation task using the Fitts' paradigm[ 37].
Specimens and power calculation : The sample size estimates/power calculations for archived FFPE specimens used in this study are based on published microarray classifier literature using standardized fold change of 2.0.
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We used PS – Power and Sample Size Calculation to calculate the sample size, which resulted in a sample size of 45 patients in each group.
Item 14: Estimated number of participants needed to achieve study objectives and how it was determined, including clinical and statistical assumptions supporting any sample size calculations "The sample size was calculated on the basis of the primary hypothesis.
As a result of these calculations, the sample size was determined to be 30 completers per group.
The calculation of the sample size is shown below.
A power analysis was performed for calculation of the sample size.
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