Exact(3)
Briefly, one-degree gridded mean values of conductivity at each standard depth were compiled after back calculation, subject to quality control procedures.
Only one subject performed below average on calculation (Subject 9).
The sample size calculation, subject selection and sample division were performed with Epidat 3.1.
Similar(57)
To assist with this calculation subjects were provided with calculators.
As the sample size was small in GOLD stage 2, for this calculation subjects with GOLD 2 and 3 were combined.
Results of interim calculations subject to review are presented.
In that study [ 27] it was shown that effect size calculation is subject to an interaction of cognitive domain, disease severity, and instruments used for assessment.
This calculation is subject to numerous inaccuracies.
Although the calculation is subject to recall bias, the index still provides one number reflecting the amount of headache the patient has, taking into account attack frequency, attack duration and cluster duration.
Moreover there is imbalance in the size of the trial arms in the included studies, so use of the raw totals for calculation is subject to Simpson's paradox as well.
Additional features of the profile are evident from an alternative estimate of position using a weighted kernel density calculation (still subject to local MNase preference uncertainty) that gave a preferred dyad position at base pair 2250 (Methods; see Additional file 1, Figure S2b), within 8 bp of the in vitro 601 dyad.
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