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The risk for exposure to a hepatitis virus or to HIV has declined by at least an order of magnitude since the calculation of this estimate, and the current cost-effectiveness would be significantly worse.
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This last interaction term allows the calculation of the estimate of 10 year decline in the five age cohorts, undertaken with the original scale for all tests.
In the meta-analysis, raw data for genotype frequencies, without adjustment, were used for calculation of the estimates of OR.
Calculation of the estimates and comparisons among groups by permutation tests (1000 permutations) were performed using fstat v.2.9.3 (Goudet 1995).
The online supplementary appendix table details the formulas used in the calculation of the estimates and their CIs.
Power calculation of this GWAS was estimated by the QpowR program (https://www.msu.edu/~steibelj/JP_files/QpowR.html) using the R package.
The coefficients in Table 3 allow calculation of an estimate of the PCS for subjects with different problems.
Numerical problems due to sparse data in the analysis including only early samples, did not allow the calculation of adjusted estimates in this subset.
This enabled calculation of pooled estimates of refractive error prevalence, with studies weighted by sample size and between-study variance and a summary estimate standard error calculated from the inverse sum of the adjusted weights.
The calculation of the Kaplan Meier estimate required for this graph is included in the Cox program.
Thus, part of the difference found between the two estimates is due to the calculation of the diary estimate.
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