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The calculation of the sample size is shown below.
A power analysis was performed for calculation of the sample size.
For calculation of the sample size, a difference of 2 ± 0.8 points in the VAS scale is considered clinically significant.
b Calculation of the sample size with the two different distributions of SL (light grey line) and a treated group (dark grey line).
a Difference between SL and TR xx at the dose-response curve (green arrow) marks the basic distance for calculation of the sample size.
Statistical calculation of the sample size was not done prior to the experiment.
The data collected allow for calculation of the sample size needed for a larger study.
DAR performed the study design and calculation of the sample size of the study.
Calculation of the sample size was based on the outcome of 'good quality care'.
The calculation of the sample size was based on a power analysis.
Simon's optimal two-stage design was used for calculation of the sample size [ 11].
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