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GAMLSS models provide exact modeling of continuous outcomes, e.g. for the calculation of standard reference values.
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The calculation is based on an approximation valid for δ <10‰: 2 3 Analytical uncertainty at 2 SD is estimated based on either replicate analysis of a standard solution (UM-Almáden) or replicate analyses of standard reference materials.
In these cases the calculation of standard errors of difference will be based on the assumption that there is no variation between the reference genotypes, and standard errors and degrees of freedom are derived from a model which omits the random factor for genotypes.
The histogram of the color bar on the reference picture was used for normalization, followed by calculation of the reference mean and standard deviation (Fig. 2).
MRI, GSUS and PDUS were used as the standard reference method for calculation of sensitivity and specificity.
For every measured ECG parameter its mean value and standard deviation (SD) were calculated and the values allowed for calculation of relevant reference norms (mean ± 2 SD) from 25 cycles.
MRI was used as the standard reference method for the calculation of the sensitivity and specificity of US, x-ray, and clinical examination [ 12].
The standard reference population of the EU was used for this calculation.
Only 1 laboratory reported on the statistical method used for calculation of the reference interval.
The initial step is the calculation of a reference state without any impairment.
These calculations can be done automatically with MACSYMA, which has become a standard reference in many theoretical-physics papers.
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