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As such, given that 1) vitamin D deficiency is the norm in hemodialysis patients, 2) vitamin D downregulates the renin-angiotensin system [ 24, 25, 35], and 3) increased RAS activity is associated with alterations in cardiac autonomic tone [ 35- 37], we feel there is sufficient justification for the sample size calculation herein.
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The calculations herein give a detailed structural and energetic picture of blocker binding to Kv1.5 and this model should thus be useful for further ligand design efforts.
The average of the longer-than-decadal-data-based annual averages since year 2000 is 2.2%% (data sources 3 and 4, Table 2), which is used in calculations herein.
All calculations herein of true and false positive rates in the presence of an alternative hypothesis use adjusted p-values.
The calculations herein might be used to deal with residual heterozygosity, but it is unlikely that it will give much improvement in the analysis.
The novel calculation presented herein justifies the use of the adipose disposition index to characterize the contribution of adipose insulin resistance to GSIS in obese nondiabetic and obese diabetic subjects.
Simplified elastic hand calculations performed herein were used to validate the FEM.
The numerical calculations described herein explicitly indicate that the perpendicular divergent ion flow can contribute to the morning–evening component of the magnetic field perturbation during magnetic storm conditions, and can result in populating the high latitude and tail regions by the energetic protons.
Furthermore, we use the value of 1.08% recovery per decade because this estimate is based on the truly global synthesis of [16], which provides necessary parity for the global scale calculations described herein.
Hence, the rMD calculations employed herein utilized an sp hybridized pyrrolidine nitrogen.
All calculations reported herein were carried out using the VASP package 23– 25 (see the Supporting Information for computational details).
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