The integral method was selected above the curl-B solution, because the requirements concerning the geometry of the four measurement points needed for the calculation of the current density is less stringent.
Another notable point is that, regarding the voltage range within which we are working, it is necessary to assume up to 2 sub-bands for the calculation of the current in the used nanoribbon which is of armchair type with N = 16, because considering the distance between the sub-bands, the second sub-band practically plays an important role in the current calculation.
For the calculation of the current and the spin-decomposed transmission spectra, that is defined as {T}_{sigma }(E =frac{1}{N_k}{displaystyle sum_k{T}_{sigma}left k,kern0.5em Eright)} (1) Table 1 Cutoff radius r c of the pseudoatomic orbitals and number of primitive orbitals for s-, p-, and d-orbitals (n s, n p, n d) r c (a.u).
In Figure 5 the results of the calculation of the current density vector field for electrons and holes in the semiconductor bulk are represented through streamlines connecting the Body with the Top contact.
This is consistent with our prior findings showing that 20 mg of oral MP did not significantly increase DA in the striatum (assessed with PET and [11C]raclopride) when given with a neutral non-task whereas it increased it when MP was administered concomitantly with a cognitive task (same numerical calculations task used for the current study)[28].
As no literature for this specific question was available for the a priori sample size calculation the sample size for the current study was chosen in orientation to other literature in the field of bowel function and gut health [ 16- 20].
For sample size calculation, the current trial used a two-stage optimal design, as proposed by Simon (1989), with a 90% power to accept the hypothesis and 5% significance to reject the hypothesis.
Similar calculations were not done for the current project, although most of the selected drugs are frequently administered in the pediatric population (based on reported evidence in the literature).
Therefore, for statistical calculations in the current phase III trial, we used the MST value of the Souhami trial for the control arm instead of the MST of the SPE regimen.
