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According to this power calculation, a total of nine subjects were needed in each of the three groups in the RCT.
After calculation, a total of 93.4% of copper was recovered from PCBs with an average processing capacity of 11.1 g PCBs/L/d.
Therefore, we included 70 hospitals for the regression calculation, a total of 2494613 admissions.
If these are included in the calculation, a total of 34% of the drug was excreted in active forms.
Following the power calculation, a total of 920 individuals were invited to participate; 568 of them accepted the invitation.
For the structure calculation a total of 279 NOEs from both Fst and Fst1−27 were used together with 49 ϕ and ψ angle restraints derived from chemical shifts using the PREDITOR webserver.
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By combining the use of popular docking scoring functions together with detailed molecular dynamics simulation and protein-ligand free energy calculations, a total of fourteen molecules are found to be potentially strong binders of PAR1.
Based on our tentative calculations, a total of eighteen clinics will be randomized equally to intervention and control groups.
Based on these calculations, a total of 34 participants (17 to each group) would be needed to provide 80% power with a 5% significance level.
Based on sample size calculations, a total of 93 subjects in each group was set as a target (significance level: p < 0.05, event rate in the UC group 0.50 and in the UCMT 0.70, power: 80% and an equal amount of subjects in both treatment groups).
We then selected random sections of 100 residues from each multiple sequence alignment, calculated the desired statistic from the resulting resampled data, and repeated this resampling and calculation procedure a total of 10 times.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com