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The AUC values are calculated using software package SPSS SPSS Inc.., USA).
The median and interquartile observer ratings were calculated for each angle and for each observer group; these descriptive statistics were calculated using software that we developed using MATLAB (The MathWorks Inc., Natick, MA, USA).
Analyte concentrations were calculated using software provided by the manufacturer (Bio-Plex Manager Software).
The low pressure UV doses were determined as previously described and calculated using software (Bolton Photosciences, Ayr, Canada) [50].
To determine the levels of significance between transgenic and control lines, Least Significance Difference (LSD) was calculated using software IRRISAT.
Mean and standard error values for rotarod scores, FITC-albumin quantification and western blot quantification were calculated using software program SigmaStat SYSTAT software Inc).
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LD50 was calculated using Prism software (GraphPad software, CA).
Solubility and supersaturation were calculated using the software package EQ3/6.
The phylogeny and coalescence times (Y axis) were calculated using the software package BEAST v.1.7.5.
Statistical power was calculated using the software TDT Power calculator [ 14].
Differential expression was calculated using Cuffdiff software included in the Cufflinks package.
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