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Sample size was calculated using a Raosoft sample size calculator.
Genetic distances were calculated using a Kimura 2 parameter method.
Significance is calculated using a Cox proportional hazards model.
Linkage disequilibrium was calculated using a custom written python script.
Vector-flow maps were calculated using a multi-angle Doppler estimation strategy36.
Post-hoc pairwise comparisons were calculated using a sequential Bonferroni correction to adjust p-values.
Statistical significance was calculated using (a) simple Mann Whitney or (c f) one-way ANOVA tests.
p-values were calculated using a two tailed, unpaired t-test with unequal variances.
Tracer concentration was calculated using a standard curve and normalized to matched controls (set to 1).
Protein concentration was calculated using a BCA assay (Pierce) following the manufacturer's protocol.
Weekly alcohol consumption was calculated using a method reported in a previous study60.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com