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Linkage disequilibrium (LD) was calculated in healthy controls.
The 95th percentile calculated in healthy donors was less than 12 pmol/L.
Pressure gradients between arm and legs have been calculated in healthy populations sample, and in those with with vascular risk factors, when the method was widely used to examine peripheral circulation [ 32].
For instance, Umhau et al. [ 62] showed that, based on PET measurements 60 minutes following administration of [1-C]DHA, the incorporation rate of DHA could be calculated in healthy human volunteers.
Serum concentrations of Zanamivir were calculated in healthy human volunteers following twice daily treatment with Zanamivir at multiple doses used in the clinic (100, 200 or 600 mg intravenous solution or 10 mg oral inhaled) and the maximum serum Zanamivir concentrations reported were between 9.83 and 45.3 ng/ml (Shelton et al., 2011).
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The radiation dosimetry for the 18F-labeled amyloid imaging agent florbetapir has been calculated in nine healthy volunteers and results in an effective radiation dose of 18.60 ± 4.26 μSv/MBq or 6.88 mSv for 370 MBq.
Strain and stress distributions in deep muscle and fat tissues were therefore calculated in six healthy subjects during sitting, in a double-donut Open-MR system, using a "reverse engineering" approach.
The normal urinary L/R, for our laboratory, calculated in 40 healthy controls is 0.045.
The reproducibility expressed as coefficient of variation (CV), measured on 5 times consecutively within 1 h with repositioning between each measurement, was 1.71% for stiffness index calculated in 17 healthy volunteers, and 0.56% for mBMD measurements calculated in a random sample of 20 of the subjects.
When the sensitivity, the specificity, negative/positive predictive values as well as LR+ and LR- of the ALS assay were calculated in comparison to healthy controls, all these parameters substantially increased as expected (data not shown).
Allele and genotype frequencies were calculated in patients and healthy controls by direct gene counting.
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