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To understand the influence of spatial scale more acutely, we calculated disease rates in individual watersheds and examined the influence of land use.
We calculated disease distribution per age group.
This may have caused a slight overestimation of our results because we may have calculated disease exacerbations or remissions as new participants.
Given the availability of lead-specific modeling tools and dose response relationships, we calculated disease incidence and DALYs from lead separately.
Although these reports and others have calculated disease burden related to poor water supply, sanitation, and hygiene there has not been a quantification of the improvement in health related outcomes due to improvements in water supply and sanitation.
We calculated disease burden based on estimated annual incidence generated through simulation of HAV transmission over the period 2000 2030, to assess the interaction between the diminishing of natural immunity in the population (i.e., the replacement of immune cohorts) and population ageing on the burden of HAV in the Netherlands.
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We also calculated disease-specific survival from the date of the first tumor resection (outside or in referral center) to the date of death resulting from disease progression or last followup.
Another study has demonstrated that calculated disease rates may vary more than 55% depending on the methods used when calculating disease occurrence in the same population.
As the DA is the smallest census unit at which census variables can be joined, they are often used to calculate disease rates.
Age at onset of disease symptoms was obtained from the CARRA Registry, which was utilized to calculate disease duration by subtracting age of disease onset from age at survey administration.
Subjects in this longitudinal cohort are sampled every 6 months, and CD4 counts measured for calculating disease progression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com