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Also shown is the theoretical expression, calculated as using (28) and the elemental distance Markov chain.

The conditional probability of Equation (9) can be calculated as using the chain rule.

If the interval of experimentation does not include the M-plateau phase, then vectorial capacity is calculated as above, using the linear function bi(N).

dsDNA concentration was calculated as copies/ul using the formula: Copies/ul  =  Xg/ul DNA ÷ (product size in bpx660)×6.022×10 23.

Spin concentrations were calculated as described using 1.00 mM CuSO4-EDTA as the standard.

The remaining values of OccX can be calculated as needed using the sampled values and BX.

LD decay for each population was calculated as r using PLINK.

Adjusted p-values for correlated genes were calculated as FDR using cor.test.

Effect sizes were calculated as SMDs using Hedges' g with 95% confidence intervals.

To estimate LD, pairwise LD was calculated as r using PLINK v1.07.

Gene-wise expression values were calculated as above, using the ML expression thresholds as determined for each sex independently.

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