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The Marshall score was then calculated, as previously described [ 15].
The cell population doubling time was calculated as previously described26.
Tumor volume (TV) was calculated as previously described6,11.
The IE index was calculated as previously described.
Tumour doubling times were calculated as previously described[11].
The %DC was calculated as previously described [12].
PSA doubling time was calculated as previously described [22].
Inhibitor kinetics were calculated as previously described (15).
Percent suppression was calculated as previously described [55].
Microvessel density (MVD) was calculated as previously described [56].
Molar extinction coefficients were calculated as previously described [5].
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