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Likewise, a FN is a pair in the correct alignment not present in the calculated alignment.
We calculated alignment scores by assigning a value of 1 for identical residues, 0.5 for a positive alignment score in the BLOSUM62 scoring matrix, and 0 for non-positive BLOSUM62 scores or a gap.
A FP is a nucleotide pair in the calculated alignment that is absent from the correct alignment.
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We score calculated alignments against the correct alignments generated during the evolution process.
The residue-residue correspondences derived from the calculated alignments allow construction of sequence motifs and profiles important for assessing regions of residue conservation.
Relatively high confidence predictions of new possible mutation points are assigned to the mutations predicted based on calculated alignments between genomes from different dengue serotypes (DENV-1, -2, -3, and -4).
Moreover, an equation used to calculate alignment parameters of the segmented parabolic mirror is presented following the same idea.
The software's default settings were used to calculate alignment scores.
k-mer searches were on average 860 times faster than blastx because the k-mer approach neither extends the matches nor calculates alignment statistics for the resulting matches.
By expressing the structural information in Spherical Harmonics (SH) Expansion, it is possible to formulate the rotational alignment as a fast rotational matching, which simultaneously calculates alignment scores of all rotations using FFT.
Maps of the a1 and a2 mating-type chromosomes were compared to each other with the MapSolver software (OpGen) to calculate alignment scores based on a cumulative scoring function that rewards matching cut sites and penalizes mismatch or missing sites.
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CEO of Professional Science Editing for Scientists @ prosciediting.com