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The upstream pathway analysis module of Ingenuity Pathway Analysis (IPA) (Build 320386 M, Version 21249400) was used to calculate upstream regulator enrichments and to determine whether the regulators identified are either in an activated or an inhibited state [ 35].
The cytosine methylation in 3k upstream of all genes was averaged to calculate "upstream" methylation levels for every gene in both AHB and EHB; the cytosine methylation levels in gene body (or exons) were averaged to calculate the methylation level of gene body (or exons).
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However, there is one exception where higher incision rates (~ 6 mm/yr) were calculated upstream of the Darvaz Fault Zone, a major tectonic feature that forms the western boundary of the Pamir.
Therefore, due to the often complex global production networks involved in producing such auxiliaries, energy carriers and grid energy, the calculated upstream GHG emissions are associated with a number of uncertainties (Table 2) [82].
For the 2- and 5-Mbp windows, distances of 1 or 2.5 Mbp were calculated upstream and downstream from the center of each gene.
If there are no recycle loops in the network so that all possible paths through the network are non-selfintersecting, this equation can be used to solve sequentially for all "downstream" fluxomers in terms of previously calculated "upstream" fluxomers.
The integrated computational framework was then used to calculate the optimal upstream interception strengths for controlling downstream flooding under hydrologic conditions associated with a 100-year return period storm.
We could not calculate a median upstream migration date for baseline wild adults because they were all sampled as they exited Forks Creek after spawning.
In this work, the SL index was calculated for the upstream sector of the Gállego River basin in the central Spanish Pyrenees to test its accuracy and sensitivity for detecting the imprints of different surface processes.
H3K4me3 ChIP read depth was calculated 2 kb upstream and downstream of gene start positions.
To obtain further insights on their relationship with promoter regions, we calculated the position (upstream or downstream) and distance of each site to its nearest TSS.
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