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To calculate denominators for the assessed indicator, facility deliveries as percentage of the expected number of births, we used the population figure estimated by the recent census and the crude birth rate of 25.9‰ for rural areas as estimated by the Cambodia Demographic and Health Survey 2005 [ 13].
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We calculated denominator degrees of freedom with a Satterthwaite [45] approximation.
We calculated denominator periods for exposed and non exposed groups by year, myopathy code and drug class.
To do this we examine the potential of a patient flow-based method for defining hospitals' catchment areas, which is practical for calculating denominator populations.
For each PCT standard infant death rates were calculated (denominator: all live births) and then recalculated excluding births where clinical decision making was most prone to variation (births <24 weeks gestation).
US Census 2000 population data, obtained using the American Factfinder Database [22] and the Integrated Public Use Microdata Series [23], were used to calculate population denominators (year 2000 data were used as denominators in all years).
The American Community Survey, a yearly demographic survey conducted by the US Census Bureau (16 ), was used to calculate population denominators for occupational data.
Survey distribution was entirely dependent on the email gatekeepers; eligible participants could have received the email from more than one source or not at all and it was not possible to calculate accurate denominators.
The calculation of incidence is sensitive to the method used to calculate the denominator.
Kenward and Roger's method (Kenward and Roger 1997) was used to calculate the denominator degree of freedom for the fixed effects.
In mixed model analyses, the Satterthwaite approximation was used to calculate the denominator degrees of freedom in the mixed models [52].
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