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The 32 kDa enamelin undergoes conformational transitions upon calcium binding.
Kreimer, G., Surek, B., Woodrow, I. E. & Latzko, E. Calcium binding by spinach stromal proteins.
Ito, D. et al. Microglia-specific localisation of a novel calcium binding protein, Iba1.
The other two EF hands have novel structural features that prevent or impair calcium binding.
Calcium binding induces these particles to clump together, making them appear darker in an MRI image.
Transgenic mice overexpressing the calcium binding protein, S100A4/Mts1, occasionally develop severe pulmonary vascular obstructive disease.
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(C Conservationof of the di-calcium binding site.
Thus, calmodulin and calcium-binding-protein bind to separate molecular brake and accelerator pedals.
The resulting protein selectively binds calcium over magnesium with calcium-binding affinity comparable to that of natural extracellular calcium-binding proteins (K d) of 50 microM).
Remarkably, the research team observed that calcium-binding-protein is still able to bind and accelerate calcium entry.
Conversely, for channels tethered to calcium-binding-protein, calmodulin was also still able to bind.
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