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Cardiac CT, which has evolved as a useful tool for the assessment of obstructive and non-obstructive plaque, has mainly been limited to the morphological assessment of CAD, i.e. CT coronary angiography [30].
According to the hypothesis to be tested, subjects with non-advanced CAD (i.e. coronary stenosis <50%) were not included in the study.
Using log-transformed data with signal intensities >80, only 19 probesets were found to be significantly differentially expressed in a multiway ANOVA (smoking, age, gender, cohort, race, CAD (i.e. case vs. control) and CAD-index as fixed factors or random effects, respectively) (table 2).
De Maio et al. [ 9] identified three groups of patients with CAD: (i) patients with atherosclerotic cardiovascular disease, (ii) women in the postpartum period and (iii) an idiopathic group.
No other associations between the investigated polymorphisms and subgroups of CAD, i.e. T2DM, MetS, previous MI and gender, were observed.
Although they excluded patients with myocardial ischemia using dipyridamole stress echocardiography, they included patients with known CAD (i.e., history of myocardial infarction, coronary revascularization and/or angiographic evidence of > 50% diameter coronary stenosis) or regional wall motion abnormalities.
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Traditional Computer-Aided Design (CAD) drawings (i.e., graphical entities such as dots, lines, and curves) and 3D models (i.e., 3D based presentations, rendering, walk-through, etc. to enhance model-based visualizations) have evolved into a new paradigm: intelligent Building Information Modeling (BIM).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com