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The univariate phase spectrum model is proved to be valid, bypassing the need of the classical spectral representation techniques in modeling the phase spectrum where hundreds of variables are required.
Most importantly, we could determine the clonal distribution of mutations, thereby bypassing the need of cloning experiments.
One of the questions that is currently addressed in our lab is whether lysosomal membrane proteins can travel directly to late endosomes or lysosomes, thereby bypassing the need of ESCRT sorting machinery.
We developed KvarQ, a new tool that directly scans fastq files of bacterial genome sequences for known variants, such as single nucleotide polymorphisms (SNP), bypassing the need of mapping all sequencing reads to a reference genome and de novo assembly.
Considered together, these results show that manipulation of cyclin D-CDK4/6 activity can be used to direct differentiation of hPSCs toward the endoderm germ layers bypassing the need of exogenous Activin and the usual variability between lines.
We also present a novel approach based on the ratio of epitope expression levels across different cell types to quickly identify binding targets of a given molecule among thousands of proteins on the cell surface, bypassing the need of pull-down experiments and mass spectrometry.
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The earlier reconstitution assays by Bien et al. support a similar mechanism, as the oxidation of both disulfides in Cox19 required only excess of oxidized Mia40 (bypassing the need for reoxidation of Mia40).
The genome sequence of Candidatus Liberibacter asiaticus was obtained using metagenomics by whole-genome shotgun sequencing of an infected psyllid (21), thereby bypassing the need for culturing of the pathogen.
For AC measurements, we evaluated basal enzymatic activity, the response to global stimulation of G-proteins by fluoride, and maximal enzymatic activity elicited by forskolin, which acts directly on AC, bypassing the need for activation of neurotransmitter receptors or G-proteins (Seamon and Daly 1986).
Thus it is possible that local PDT treatment of tumours leads to release of factors capable of bypassing the need for CD4+ T cells in the activation of DCs.
"This is a cheaper way to get information back to the power stations, bypassing the need for physical installation of smart meters".
More suggestions(16)
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