McColley did take part two years ago in studies of denufosol, a drug produced by the biotech company Inspire that works in a different way from the Vertex and PTC drugs, by stimulating an alternative-chloride channel and bypassing the effects of the genetic mutations entirely.
Some of these questions may be solved through bypassing the effects associated with fluid-filled systems and measuring IAP with a balloon-tipped catheter.
A 3 × 3 Latin Square experiment was designed to compare 2 ways of bypassing the effects of the rumen with olive oil fatty acids in 'Manchega' dairy ewes.
This suggests an interplay between ER-α and ERBB2 receptors in the context of bypassing the effects of drug treatment.
These findings are in keeping with recent advances in the understanding of iron metabolism; intravenous iron is more effective than oral iron, particularly in the setting of acute or chronic inflammation, by bypassing the effects hepcidin an inhibitor of gastrointestinal iron absorption.
In the case of rivaroxaban, it is also conceivable that PCC or aPCC might be effective since they would bypass the effect of FXa inhibition.
However, alternative geranylgeranylation has been postulated as an escape mechanism by which RAS bypasses the effect of FTI treatment.
(E ) A constitutively active form of Stat3, Stat3C bypassed the effect of miR-9 inhibition on astrocyte differentiation.
Importantly, addition of AICD peptide to γ-secretase inhibitor-treated SH-SY5Y cells bypassed the effect of the inhibitor and completely restored PGC-1α mRNA levels (Fig. 3D).
