Because this chromatin signature does not require polymorphisms or monoclonal cell culture, it bypasses limitations of other approaches relying on direct measurement of allelic expression, and allows the investigation of genome-wide MAE patterns in vivo.
The advisory group structure serves one useful purpose: bypassing the limitations placed on political activity by government employees.
The use of an actively mixed flow reactor results in a uniform concentration of reactants at the catalytic material surface at high conversion factors which also allows to measure the photocatalytic activity bypassing the limitations imposed by the concentration gradients of unmixed flow reactors.
They say the speed increase is due to "bypassing the limitations of the TCP protocol".
Some of the earliest examples include Perfect Dark on the Nintendo 64 system, which included the feature as a means of bypassing player limitations on such pre-Internet enabled consoles.
Third, an intracellular genetic selection can directly assay for effects on enzymatic activity, bypassing inherent limitations of in vitro assays.
An illumination method is presented that produces an incoherent pattern through interference, bypassing the limitations imposed by the aberrations of the condenser lens and thus enabling axial sectioning in non-fluorescent imaging.
This will most likely require bypassing the limitations mentioned above, for example by substituting SNP arrays by Genotyping By Sequencing techniques and radiation hybrids by other chromosome breaking mechanisms such as genetic recombination in large samples.
Specific protein binders can thus be selected in vitro and used to reprogram developmental systems in vivo directly at the protein level, thereby bypassing some limitations of approaches that function at the DNA or the RNA level.
We chose to adopt the Gateway system to bypass the limitations of restriction enzyme mediated cloning.
Thus, zebrafish presents a significant model for faithfully reflecting the in vivo status of Ras signaling, bypassing the limitation by their over-expression that might re-route them to ectopic compartments.
