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In this study, we investigated whether PCL/collagen scaffolds could support cell growth and withstand physiologic conditions while maintaining patency in a rabbit aortoiliac bypass model.
The Dyson creep model is a microstructure-based climb-glide bypass model for unimodal distributions that links microstructural evolution (e.g. evolution of the particle dispersion) to the creep rate.
The mechanistic creep model is based on fundamental dislocation creep mechanisms – the particle bypass model based on dislocation climb from Arzt and Rösler [1] - that describe the steady state creep strain rate as a function of stress, temperature, and microstructure.
Although the aortic interposition bypass model has been widely used to evaluate biomaterials for bypass grafting, there is no comprehensive description of the procedure or of the distribution of intimal hyperplasia that results.
Objective to investigate the effect of clopidogrel combined with aspirin or aspirin alone on fibromyointimal hyperplasia (FIMH) in a bypass model with native vein grafts (NVG) and biocompound grafts (BCG).
Methods: The intima-adventitia (n = 28) and conventional anastomoses (n = 28) were evaluated intraoperatively (n = 56), at 4 hours (n = 20), and at 5 weeks (n = 36) in a new off-pump low-flow (n = 28) and high-flow (n = 28) porcine bypass model (≤15 mL/min and about 60 mL/min, respectively).
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However, there are no studies reporting the role of DADLE, a δ-opioid receptor agonist, in cardiopulmonary bypass models during cardiac surgery.
When the bypass flow model was added to MARS-LMR, the RMS error for type A reduced to 12.6%.
Human Pol κ is unable to bypass a model thymine dimer in vitro; however, it can extend a primer bearing a 3'-dG 3'-dGed opposite the 3'-dT of a modelocatedne cycloppositedimer in vithe [14].
Furthermore, it was recently reported that both E. coli DinB [8] and human Pol κ [9], [53], catalyze bypass of model N2-dG–N2-dG N2-dGstrand cross-linterstrandro.
DNA polymerases of the DinB family, pol IV in E. coli and pol κ in human, are implicated in error-free bypass of model acrolein-mediated N-dG secondary adducts, the interstrand cross-links, and the peptide conjugates.
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