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Despite these similarities, iPSC-Mac exhibited a stronger response to pathogen stimulation as demonstrated by whole transcriptome analysis, further favoring their application as a cellular therapeutic for the treatment of bacterial infections.
The components of miRNAs regulatory network at the transcriptional and the protein level have been also revealed by whole transcriptome analysis and Tandem Mass Tag in transfected GBM cells.
We explored the potential roles of miR-29a in T-ALL, through the introduction of synthetic miR-29a mimics into Jurkat cells followed by whole transcriptome analysis.
By whole transcriptome analysis, we compared set of genes increased in cortical and hippocampal regions and we identified the HtrA1 gene product that belongs to a family of genes that were firstly identified in bacteria.
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Yet, the number of detected proteins was significantly lower than the number of transcripts (approximately 16,457 genes) in mature mouse oocytes analyzed by SOLiD whole transcriptome analysis [ 14].
The expression levels of CGs and CCGs were evaluated by a whole transcriptome analysis through Next Generation Sequencing in normal primary human fibroblasts and fibroblasts of patients affected by HS before and 24 h/144 h after IDS treatment.
Encouraged by this, whole transcriptome analysis for miRNA targets in rice transcriptome sequences was carried out, excluding those sequences on which the above mentioned analysis had been performed already in order to avoid redundancy, looking for new targets and save time.
For this purpose, two commonly used and phenotypically diverging laboratory strains, S288c and Σ1278b, were investigated by means of whole transcriptome analysis.
Cell cultures were treated in triplicate with 1 µM erlotinib for 6 hr, followed by mRNA isolation and whole transcriptome analysis (Affymetrix U133 Plus 2.0 expression arrays) (Rothenberg, 2015).
They are produced in both eukaryotes and prokaryotes and represent the vast majority of all transcripts in a cell as demonstrated by genomic tiling arrays, whole transcriptome analysis, reverse transcription-RCR (RT-PCR) and computational prediction [ 14- 26].
This study is limited by its exclusive focus on whole transcriptome analysis; we recognize the need to integrate DNA sequence analysis in future projects.
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