It is tempting to regard the cyclical structure of human history, whether the business cycle or the war cycle, as a process by which the consequences of bad decisions accumulate until some kind of crisis point is reached.
Applying multiple analytic approaches, we describe a novel mechanism by which the deleterious consequences of mutant COMP retention results in upregulation of miR-223 disturbing the adipogenesis - osteogenesis balance.
Consistent with the view that consciousness and action may be closely related, brain imaging studies have shown that delusions of control, often seen in schizophrenic patients, are associated with a failure in the mechanism by which the predicted consequences of an action are linked to the intended sequence of motor commands (Frith et alia 2000).
The emergence of health maintenance organizations – HMOs – has been an alternative of shared responsibilities by the users and service providers, a way by which the agents share the consequences of increased expenses (cutting harmful incentives granted to third-party payments).
Our study proposes phenotype changes and functional consequences, by which the inhibitory effects of EGCG on CSC properties of NPC are seen.
Remarkably, a few of the detected gene expression differences have been linked to phenotype, providing a mechanism by which the inversion could have functional consequences.
Alternatively, OA1 could counteract the capture of melanosomes by the AF system and as a consequence enhance the frequency by which the organelles move along MTs (11, 31), while in the absence of OA1 melanosome entrapment by the actin network at the cell periphery would prevail.
The drug response signatures reproduced the Connectivity Map concept initially developed by the Broad Institute 25 in which the genomic consequence of drug exposure is used to connect drug effect to disease signatures.
Similar studies are also required about the mechanisms by which such consequences can best be prevented or alleviated by more rigorous epidemiological studies.
In the publication, A Monetary History of the United States, 1867 1960 by Friedman and Anna J. Schwartz, they argue that the Great Depression was caused by monetary contraction, which was the consequence of poor policymaking by the Federal Reserve System and the continuous crises of the banking system.
