Further studies are necessary to validate our findings, as well as to elucidate mechanism(s) by which LINE-1 hypomethylation affects tumor malignant behavior.
The extent to which line-by-tester interactions contribute to low predictive ability warrants further research.
The life-cycle of a process or a task is propelled by transitions of which Line 16 shows an example.
If that is the process by which cell lines are developed, then the contributions of the extinct subpopulations would be largely unaccounted for in cell line models.
The paralogs may present alternative routes by which parasite lines carrying different pfcrt alleles could mediate this essential function.
The flow of water through the sponge is unidirectional, driven by the beating of flagella which line the surface of chambers connected by a series of canals.
Estrogens are produced by granulosa and interstitial cells, which line the egg-containing ovarian follicles.
This movement also propels the wax - produced by the modified sweat glands which line the ear canal - towards the outside.
Skidding costs are influenced by previously mentioned variables among which line length is the most important.
Experience has shown that there is no formula by which that line may be plotted with precision in advance.
