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However, the molecular mechanism by which it modulates a chemotherapy response has to be further verified.
Identifying the determinants of SYT-SSX2 recruitment would reveal crucial details concerning the mechanism by which it modulates transcription.
Although COE has been reported in various bioactivity assays, the molecular mechanism by which it modulates the EMT-mediated alteration of human gastric cancer cells has not been elucidated so far.
The inability of Snl1-L overexpression to cure [URE3] could be because it is anchored on the nuclear and ER membrane or the manner by which it modulates Hsp70 activity.
Although the dogma in the CTGF literature suggests that all of the biological responses to CTGF are mediated by the direct interaction of CTGF with cytokines or receptors, the mechanisms by which it modulates cell function are likely to be more complicated.
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A mature miRNA regulates the post transcriptional gene expression by targeting certain mRNAs, subsequent to which, it modulates multiple signaling pathways, biological processes and patho-physiologies.
The mechanism by which Id3 modulates apoptosis in malignant keratinocytes appears to be different from that of nontransformed keratinocytes.
Regardless of the complexity of the mechanism of action by which CTGF modulates cell biology, it is very clear that CTGF plays a central role in diseases in which tissue remodeling occurs.
However, the molecular mechanisms by which Atmin modulates lung development and its transcriptional targets are not yet known (30).
Thus, it is not inconceivable that the mechanisms by which MDM2 modulates lung cancer risk can differ between populations.
Mechanism by which VNS modulates neutrophil granulocytes should be further analyzed in future studies.
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