MDD patients are believed to express a heightened responsiveness to negative emotional stimuli and a reduced detection of positive affect [ 66, 67], which is explained by hyperactivity of the affective neurocircuitry, including the amygdala [ 68].
In this region, the simulation shows the emergence of a new mode of the activity, which is characterized by the hyperactivity of the DLPFC and the hyperactivation of the D1 receptors.
Both depression and anxiety disorders have been associated with hyperactivity of the amygdala and converging evidence demonstrates that one mechanism by which SSRIs may exert their action is by constraining such overactivity.
And this idea is supported, too, by "positive" disorders — excesses or distortions of function produced by hyperactivity of the same area.
This interpretation has been corroborated by neuroimaging data showing hyperactivity of the ACC in OCD patients which was positively correlated with symptom severity [58], [59].
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental condition, defined by patterns of inattention, impulsivity and hyperactivity, which affects approximately 5%% of children [ 1, 2] and 2.5 % of adults worldwide [ 3].
SLE is characterized by dysregulation of the immune system that involves hyperactivity of T cells and B cells, production of pathogenic autoantibodies, and the formation of immune complexes, which can lead to multiorgan damage.
The proposed mechanism is the induction of hyperactivity of N-methyl D-aspartate (NMDA) receptors by hypoxia, which induces hallucination and might induce NDEs [ 10].
There is more to captaincy than hyperactivity, which might be one of several reasons why Warne never achieved his dream of leading Australia.
Hyperactivity of the cycle could generate mitochondrial ROS by delivering electrons to O2 [ 44].
