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The prime targets for the discovery of functional proteins are those which show homology to counterparts in lower species by way of sequence similarities and domain conservation.
The virtual evidence from ORFinder and ScanProsite described above, by way of sequence analysis and a protein domain database query is significant but the true characterization of a protein must be done through studies of expression and other functional tests.
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It was first notice in a study by Pereira et al. [19] by way of sequencing several small coding region mtDNA segments, the presence of the coding region variant C4952T in ∼6% of their samples from the Basque Country.
Methods for the discovery of novel alkyl sulfatases are described by way of sequence-based search and enzyme induction.
Molecular dissection of this distinct flower for identifying the genes responsible for its aroma by way of expressed sequence tags (ESTs) has not been initiated in spite of its economic viability.
The close physical proximity of the PriS and Gins51 ORFs suggests a simple mechanism for the acquisition of the CTD by PriS by way of straightforward sequence duplication and deletion.
Progression through the game's storyline is largely developed by way of scripted sequences, although pre-rendered cinematic cutscenes are also used.
In the second case, we first detected, by way of Sanger sequencing of PCR products, only one heterozygous missense mutation.
It was expanded by way of a dream sequence using music from another Leoncavallo opera, "Zazà," once as popular as "Pagliacci" but now almost completely obscure.
By way of complete genome sequencing, Achilli et al. [1] identified numerous sub-branches of haplogroup H.
In addition, we have characterized, by way of complete genome sequencing, a new autochthonous clade of haplogroup H in the Basque country, named H2a5.
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