However, in all epidemiological studies there are uncertainties created by variations in registration methods.
However, comparisons of incidence rates for IS among different regions should be careful as these rates may be affected by variations in study methods, differences in genetic and lifestyle factors, and health care practices.
A further strength is that by requesting that study authors perform their analyses in a standardised way, we have been able to limit the possibility that heterogeneity between studies is explained by variation in analytical methods, which may occur when using only published results.
Results were substantively unchanged by variation in the methods used to construct the normative DTI connectome, such as excluding basal ganglia (Hagmann et al., 2008), or building a weighted network where the strength of each edge was weighted by the number of tractographic streamlines connecting the two nodes (Supplementary Fig. 6A).
Finally, the widespread use of flow cytometry for the detection of neoplastic cells in the CSF is limited at this point by variations in the equipment and methods.
The robustness of an analytical procedure is a measure of its capacity to remain unaffected by small, but deliberate variations in method parameters and provides an indication of its reliability during normal usage [16].
The robustness of an analytical procedure is a measure of its capacity to remain unaffected by small but deliberate variations in method parameters.
Comparing expression among libraries of these two species is complicated by variation in library preparation methods, notably the requirement to include an amplification step to clone cDNAs from the low levels of Pt teliospores, and the need to normalize libraries being compared to correct for EST pool size.
Published findings are mixed for fractures at other sites, and comparisons across studies are limited by the variation in the methods used to describe physical activity.
Making a valid comparison of the present seroprevalence data with those recorded in previous studies is hampered by the variation in detection methods (ELISA or WB) and cut-off titers employed and by the general difficulty in exploring the relationships among titers, infection, and clinical disease [ 3, 5, 19].
