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False negatives may also result from the reliance on individual event terms and the risk that a signal is diluted by variations in coding.
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Evolution is brought about by variations both in coding sequences and in gene expression.
Variations in coding application were discussed and consistent definitions agreed upon.
This difference does not appear to be caused by variations in the coding sequences of the two genes: replacing the RPL7B sequence with that from RPL7A does not alter the cellular localization of the protein encoded at that locus (Kim et al. 2009).
Their function might be changed by variation in genes coding for nAChRs, and especially reduced nAChR function may predispose to ND [ 38, 39].
When the data were stratified by season, no variation in coding across the 6 indicators of face validity was seen.
Besides variation in the mean number of diagnoses coded by hospital site, no other important variation in coding across the other 5 indicators of face validity was demonstrated.
However, our results do not indicate variation in coding validity by season, which would be expected if the Health Records Department was consistently understaffed at specific times of the year or if coders had especially high workloads before the end of the fiscal year in March.
The parthenocarpic potential appeared to be controlled by a single recessive gene, but no variation in coding sequence was observed in a candidate gene CaARF8.
Usually genome searches that aim to find variation in coding sequences focus on translations since non-synonym amino acid variation is generally believed to produce phenotypic variation.
Incidence and prevalence estimates of diseases based on hospitalisation diagnoses as well as results of health services research studies based on these data may be influenced by regional or temporal variations in coding of the diagnoses.
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