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Common variable immunodeficiency is a primary immunodeficiency (PID) characterized by variable age of onset of symptoms, recurrent severe bacterial infections, increased incidence of autoimmune disorders and malignancy.
HD is characterized clinically by variable age of onset (normally between 40 and 50) and severity that correlate directly with the length and the gene dosage of the CAG repeat number (Duyao et al, 1993).
HSP is a hereditary disease caused by mutation in any of more than 40 genes, and is characterized by variable age of onset and severity, thought to be due to differences in genetic background.
The disease was characterized by variable age of onset (late teens to early fifties) and severity, and by invariant initially exclusively distal leg weakness and wasting, which later spread from distal to proximal muscles of upper and lower extremities, and beyond, eventually involving most muscle groups including facial and bulbar muscles.
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The latter is characterized by a variable age of onset and shows a greater temporal fluctuation in symptom severity, and these individuals might not eventually develop full-blown psychosis.
Further tests of the hypothesis of mutation accumulation might more fruitfully focus on diseases 1) epidemiologically characterized by a very late and/or less variable age of onset and/or 2) with an abundance of common and ancient alleles.
MPS I is a rare panethnic genetic disorder characterized by a spectrum of disease with variable age of onset, progression, and organ involvement.
The study also revealed that the nosocomial variable, numbers-of-hospitalisations is the best measure of time in relation to diagnostic stability, and that the variation in numbers-of-hospitalisations itself may be explained by the variables age-of-first-admission, civil-status, first-diagnosis-being-schizophrenia and somatic-comorbidity.
Although the expression level of a gene is affected by a large number of variables (age of the organism, the position within the organism, phase of the cell cycle, environmental stress, etc).
The histological confirmation of dilated "clustered -shaped myometrial arteries partially oclustered -shapedi of variable "age" together with the presence of endovascular extravillous trophoblasts confirmyometrialgnosis.
The histological confirmation of dilated and "clustered -shaped myometrial arteries partially oclustered -shapedi of variable "age," together with the presence of endovascular extravillous trophoblast, confirmyometrialgnosis.
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