Sentence examples for by utilizing small molecules from inspiring English sources
Subsequently, we inhibited the class I PI3K pathway at different levels by utilizing small molecules inhibitors ZSTK474, KP372-1 oRapamycinin to specifically target pan-class I PI3K, Akt and mTOR respectively.
In this study, we examined the importance of the class I PI3K/Akt pathway in promoting tumourigenicity of canine cell lines by utilizing small molecules ZSTK474, KP372-1 and Rapamycin that selectively inhibit class I PI3K, Akt and mTOR, respectively.
When utilizing small molecules for biological studies, it is always assumed that the molecules are chemically inert.
Two pharmacological approaches are being developed, one involving mRNA silencing by selective short interfering RNAs (siRNA) molecules and the second utilizing small molecule drug design.
"Other people have utilized small molecules, but the performance was far below that of polymers," he says.
Nanotherapeutics commonly utilizes small-molecule drugs, peptides, proteins, and nucleic acids loaded in nano-scale carriers such as nanoparticle (NP) made of organic polymers, inorganic particles, biological lipids, and so on.
This indicates potential therapeutic efficacy utilizing these small molecules in the treatment of chemorefractory myeloma patients.
Through the combination of CRISPR and squads of CRISPR-associated – "Cas" – proteins, bacteria are able to utilize small customized RNA molecules to silence critical portions of a foreign invader's genetic message and acquire immunity from similar invasions in the future by "remembering" prior infections.
Internal cavitations at the nano/microscale can be utilized in transporting small molecules as well [40-42] [40-42]
In another study reported by Sham, Xing and coworkers, rapid structure-based virtual screening and hit-based substructure search were utilized to identify small molecules that disrupt Keap1 Nrf2 PPI.
With the exception of a recent report demonstrating inhibition of Dicer's function by small molecules, in vitro assays utilizing purified recombinant RISC factors have not been previously reported.
