Sentence examples for by utilizing a gene from inspiring English sources

In this study, to address this challenge, we purpose a four-step filtering method that predicts gene markers from RNA-sequencing data of mouse knockout studies by utilizing a gene regulatory network constructed from omics data in the public domain, biological knowledge from curated pathways, and information of single-nucleotide variants.

Pharmacogenetic research focuses therefore on identification of specific genes that influence drug response by utilizing a candidate-gene approach [10], [11], although supporting evidence for a role of these genes in development of obesity and associated metabolic traits from population-based observational studies is sparse.

Transcriptional control of a gene is often studied by utilizing a fusion of the gene's promoter with a reporter gene [chloramphenicol acetyRransferase (CAT), green fluorescent protein (GFP), and so on].

Consequently, computational methods play an important role in prioritization and identification of the most likely disease-associated genes by utilizing a variety of data sources such as gene expression [ 3, 4], functional annotations [ 4- 7], and protein-protein interactions (PPIs) [ 3, 8- 14].

Since the incomplete repression of promoter presents a major problem when cloning genes that encode lethal product to the bacterial host [ 11], it is obviously critical to tighten the control of gene expression by utilizing a tightly controllable promoter that permits E. coli normal growth until the very moment of highly toxic gene induction.

We calculate the coexpression between two genes by utilizing a mixed-model framework.

To perform this work, we enumerated all of the substrings of length L from the list of excluded-genes by utilizing a sliding scan.

The second generation of plants was screened to assess the amount of polymorphism that has been generated and now mutations can be identified in candidate genes by utilizing an approach to genetic analysis called TILLING (Targeting Induced Local Lesions IN Genomes), which was first applied in plants by McCallum et al. (2000).

We utilized a gene set identified by Camp and colleagues [ 5] to directly test whether the cocultures upregulated basal-like microenvironment characteristics.

mAPC is different from traditional clustering methods in terms of constructing co-regulated gene modules by utilizing both microarray gene expression data and motif binding information.

We evaluate our method further by utilizing replicate gene expression datasets.