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The structures, supported by biochemical experiments, reveal how eIF2D emulates the function of several canonical translation initiation factors by using three independent, flexibly connected RNA binding domains to simultaneously monitor codon-anticodon interactions in the ribosomal P-site and position the initiator tRNA.
However, it should be emphasized that the measurement uncertainty of the 3P-KMA outcomes may be expected to be lower than that of the 5P-KMA one because Ki and kb from 5P-KMA has to be computed by using three independent kinetic (micro parameters (Eqs. 4 and 5).
We have attempted to minimize this concern by using three independent intensivists in the classification process.
Similarly to [ 18], relaxation of the irreversibility constraints on existing reactions in the model can be checked by using three independent methods.
We investigated the effect on Igf2 mRNA levels during MGR knockdown by using three independent endoribonuclease-prepared small interfering RNA (esiRNAs; Kittler et al, 2007).
Another web-based program, ConoDictor, overcomes the issue of missing signal regions by using three independent sets of models built from signal, pro- and mature regions of conopeptides respectively [ 40, 41].
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Confounding effects due to transcription factor binding sequence information were estimated by using two independent motif-based algorithms followed by a variable selection method.
The role of nitrogen and iron in the generation of catalysts for oxygen reduction in acidic media has been investigated by using two independent organic precursors.
By using two independent detection approaches, we identified novel candidate substrates for SETD6, and verified that all targets tested in vitro and in cells were genuine substrates.We describe a novel proteome-wide methodology for the identification of new PKMT substrates.
Each experiment was performed in duplicate by using two independent cultures.
Furthermore, by using two independent datasets, we provide evidence that better educated Indian households whose first two children are male do have strong preferences for a balanced family.
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by using three network-coded
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