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Quantitative PCR was done by using the Maxima SYBR Green/ROX qPCR Master Mix Life Technologiess) and the MX4000 instrument (Stratagene, Basel, Switzerland), according to the manufacturer's instructions.
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In the case where the true path delay is different from integer times of delay samples, by using the maxima-searching method, large estimation errors are resulted.
We estimate the parameters by using the maximum likelihood method.
Specifically, both the amplitudes become 1.0 by using the maximum value over the last half-period.
Furthermore, the uniform validity of the solutions is proved by using the maximum principle.
The uniform validity of the solutions is proved by using the maximum principle in Section 3.
The obtained results are compared with those results obtained by using the maximum power criterion.
The different parameters are estimated by using the Maximum Expectation of joint Likelihood criterion.
The parameters α and β can be easily estimated by using the maximum likelihood technique [42].
It is not difficult to prove this result by using the maximum norm.
Fig. 3. Final hypocenter distribution (March 15th June 18th , 2011 derived by using the maximum-likelihood estimation technique with bathymetry.
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