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UniProt identifiers were mapped to HGNC identifiers using the cross references in the full UniProt entries.
This was done using the cross-referencing provided by the FANTOM Consortium and DisGeNET, a number of controlled vocabularies, including UMLS [ 34] and Uberon [ 33], the MeSH database and manual curation.
The lists of detected peptides were converted to a list of corresponding unique genes using the cross-reference table provided by NCBI (ftp://ftp.ncbi.nlm.nih.gov/gene/DATA/gene2accession.gz).nih.gov/gene/DATA/gene2accession.gz
Several issues need to be considered in order to use the cross-referencing method properly.
To do this, we used the cross-reference database developed by Martin 36 that relates each PDB entry with one or more protein sequences from UniProtKB.
Inside the obo file one can also reference terms defined in other ontologies by using database cross reference ("dbxref") lists.
The same results (e.g., Figure 5) will be obtained for the level-crossing converter when the number of quantization bits is 9, 7 and 5. On the other hand, by using the delta level-crossing, the number of reference levels is decreased to 105 (7 bits), 25 5 bits) and 7 (3 bits).
We have addressed the cross platform/cross species comparison by using the zebrafish transcriptome as a reference.
These results were then referenced for similarity of known porcine proteins by using the Applied Biosystems GPS Explorerr software version 3.6 prior to being submitted for cross reference with the NCBInr mammalian protein database.
The Swedish PHC version of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision [ 24], was mapped to the full version of the classification by using a cross-reference scheme based upon equivalent tables from the National Board of Health and Social Services.
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