Tissue specificity of a gene is measured by using tissue specificity index τ.
Cell-specific gene expression analysis was performed by using the specificity index statistic (pSI) R-package version 1.1 (Dougherty et al., 2010).
Secondly, we separately filtered search returns for longitudinal observational studies in Embase and Medline by using "prognosis-specificity" database specific filters and in Web of Science by using text words relating to the study design.
We assessed overall model discrimination by using sensitivity, specificity and the area under the receiver operating characteristic curve (AUC).
The performance of the Thai version of CAM-ICU algorithms was calculated by using sensitivity, specificity, and predictive values (positive predictive value and negative predictive value).
The diagnostic performance of the e-model on identification of diabetes status was evaluated first by the inter-rater agreement between e-model classification and physician classification of diabetes status using the kappa statistic and second, by using sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV).
20 In the second scenario (scenario ii) we investigated the impact of our assumption that MRI targeting has no impact on men without clinically significant disease (by using a specificity of 80% for MRI-targeted biopsy as reported by Kasivisvanathan et al 19 rather than our base case estimate of 90%).
However, a wider group of people with high risk of specific CVDs could be targeted and treated earlier by increasing the sensitivity (by extending the time horizon to lifetime, as suggested by the Joint British Societies latest recommendations) and specificity (by using more specific diagnoses) of risk predictions.
Narlikar et al. 2010 employed LASSO regularization to identify heart-specific enhancers by using TF binding specificities from PSSMs as features [ 81], our approach in contrast used non-TF chromatin-associated features from ChIP-Seq data to identify enhancers.
Clinical parameters capable of identifying patients most and least likely to have hepatotoxicity were evaluated by using sensitivity and specificity testing.
